Viral infection of the thymus

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Viral infection of the thymus.

We have examined infection of the thymus during congenitally acquired chronic lymphocytic choriomeningitis virus (LCMV) infection of mice, a classic model of antigen-specific T-cell tolerance. Our results show that (i) infection starts at the fetal stage and is maintained throughout adulthood, and (ii) this chronic infection of the thymus can be eliminated by transfer of virus-specific cytotoxi...

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ژورنال

عنوان ژورنال: Journal of Virology

سال: 1992

ISSN: 0022-538X,1098-5514

DOI: 10.1128/jvi.66.5.3155-3160.1992